Alzheimer’s Drug Discovery Foundation Raises $1.1M for New Clinical Trial in Alzheimer’s


Drug Could Be the First to Slow the Progression of Alzheimer’s Disease

The Alzheimer’s Drug Discovery Foundation (ADDF) announced today that it raised more than $1.1 million in support of a clinical trial to test an existing drug for the treatment of Alzheimer’s disease.  The $1.1 million was generated during the “Fund a Scientist” auction at its Eighth Annual Connoisseur’s Dinner on May 1, 2014, and awarded to Jeffrey Cummings, MD, director of the Cleveland Clinic Lou Ruvo Center for Brain Health in Las Vegas, Nevada and Cleveland, Ohio. Dr. Cummings will investigate rasagiline, an FDA-approved treatment for Parkinson’s disease with the potential to be the first drug to slow the course of Alzheimer’s disease.

ADDF Launches New Cognitive Vitality Site to Meet Critical Need in Alzheimer’s Prevention


Resource Will Provide Comprehensive Overview of the Science for Prevention Therapies

The Alzheimer’s Drug Discovery Foundation (ADDF) announced today the launch of Cognitive Vitality, a new online resource developed to provide a comprehensive and credible overview and analysis of the science for specific strategies to prevent Alzheimer’s and related dementias. The resource showcases the strength of the science for and against prevention strategies related to nutrition and the management of other diseases, to enable people to make informed decisions in protecting their brain from cognitive decline, Alzheimer’s and other dementias.

Leading Foundations Partner to Accelerate Critical Biomarker Research in AD and Related Dementias


Outcomes Could Lead to Development of New and Cost-Effective Tools for Early Detection

The Alzheimer’s Disease and Dementia Initiative (ADDI) at the New York Academy of Sciences (the Academy) in partnership with the Alzheimer's Drug Discovery Foundation (ADDF), and with generous support by AstraZeneca, Janssen, Lilly, Merck, and Takeda, has awarded a $140,000 challenge grant to Blaine Roberts, PhD, Head of the Metalloproteomics Laboratory at The Florey Institute of Neuroscience and Mental Health in Australia. Dr. Roberts will be conducting research to validate a developmental blood test for Alzheimer’s disease.

New Partnership to Provide Drug Discovery Resources for Neurofibromatosis Research Community


The Alzheimer's Drug Discovery Foundation (ADDF) and the Children's Tumor Foundation (CTF) today announced a partnership to provide CTF's scientific network access to a virtual network of drug discovery experts and contract research organizations (CROs) through the ADDF ACCESS program. CTF's mission is to find effective treatments for the genetic disorder neurofibromatosis (NF), which can cause tumors to grow throughout the body and affects one in 3,000 people. Through the effective selection of CROs and use of their services, NF researchers may be able to accelerate their research and bring novel therapies to patients faster.

ADDF and AFTD Award Grants Funding Research on Investigational Therapies to Treat Dementia


The Alzheimer’s Drug Discovery Foundation (ADDF) and The Association for Frontotemporal Degeneration (AFTD) announced today the recipients of their seventh annual partnership awards program to accelerate drug discovery for frontotemporal degeneration (FTD), a devastating form of dementia characterized by profound changes in behavior, personality, language and movement. Jeffrey Rothstein, MD, of Johns Hopkins University School of Medicine and Donald Lo, PhD, of Duke University Medical Center were each awarded $150,000 to conduct new research focused on developing novel drugs to treat FTD.

ADDF and FMM Partner to Support Novel Research for Mitochondrial-Directed Therapies


Research could lead to development of new therapies to treat a variety of mitochondrial diseases, including Autism, Alzheimer’s, Parkinson’s and Lou Gehrig’s disease

The Alzheimer’s Drug Discovery Foundation (ADDF) and the Foundation for Mitochondrial Medicine (FMM) announced today that they have awarded $200,000 in funding to James Bennett, M.D., Ph.D. to further research gene therapy of mitochondrial protein in the brains of mice with experimental Alzheimer’s disease. Bennett is studying rhTFAM, a novel human mitochondrial protein shown to increase mitochondrial function in cell and animal models. The protein has shown to restore memory function of aged mice while increasing mitochondrial function in brains, suggesting it has great potential to do the same in humans with impaired cognition and early Alzheimer’s disease.

ADDF and W. Garfield Weston Foundation Collaborate to Fund Clinical Trial in Alzheimer’s


The Alzheimer’s Drug Discovery Foundation of Canada (ADDF-Canada) and The W. Garfield Weston Foundation today announced a new funding collaboration to support a clinical trial investigating the potential for hypertension drugs to slow Alzheimer’s disease progression. The trial will be led by Dr. Sandra Black and the Toronto Dementia Research Alliance at the University of Toronto.

Foundations Partner on $3M Initiative to Accelerate Research + Discover Treatments for Alzheimer’s


Research to Focus on Repurposing Drugs for Alzheimer’s Disease and Related Dementias

Today the Alzheimer’s Drug Discovery Foundation (ADDF) and the Alzheimer’s Society (UK) announced a new partnership that will provide funding for research in Alzheimer’s disease and related dementias, with the goal of accelerating critical development programs and bringing new treatments to patients. The partnership intends to fund projects up to $1.5 million each focused on drug repurposing, leveraging existing scientific evidence and research to accelerate the drug development process.

ADDF Expands its ADDF ACCESS Program to Improve Quality and Efficiency of Drug Research


The Alzheimer’s Drug Discovery Foundation (ADDF) announced yesterday the launch of its newly expanded ADDF ACCESS program to provide scientists in academia and small biotechnology companies with access to a virtual network of drug discovery experts and contract research organizations (CROs) that have experience developing therapies for neurodegenerative diseases. Through the effective selection of CROs and use of their services, researchers may be able to accelerate their research and bring novel therapies to patients faster.

The ING New York City Marathon: Who Runs? Chris Johnson.


Why Run? To raise awareness and money for the Alzheimer’s Drug Discovery Foundation.

What for? To honor his father, New York Giants Running Back, Ron Johnson, diagnosed in 2008 with early-onset Alzheimer’s disease…

New York N.Y. October 24th,  2013. This is one story of a runner with a reason. Thirty-one year old Chris Johnson, son of legendary New York Giants Running Back, Ron Johnson has taken up the cause to find the prevention, treatment and ultimately cure for a disease that once upon a time was as mysterious and taboo as cancer used to be. Why?

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