Brain injuries from falls and accidents can remodel the brain in ways that make it more vulnerable to long term cognitive impairment.
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Depression may have a bidirectional relationship with dementia, and the role of antidepressants in protecting against or accelerating cognitive decline is complex.
E-cigarette aerosols can contain high levels of metals and other toxins known to harm the brain.
A large randomized controlled trial in the US reported that lifestyle changes can significantly impact cognitive health.
Elevated triglyceride levels in midlife are associated with higher risk for cognitive decline in later life, though this association is more robust in some populations than others.
In older adults, visit-to-visit variability in cholesterol levels may be a predictor of future cognitive decline.
A follow-up of a clinical trial reported that hormone replacement therapy started early in menopause does not have long-term cognitive effects.
High LDL-cholesterol can negatively impact brain function and increase the risk for dementia.
Features associated with climate change such as extreme heat and storms can stress the brain in ways that impair its function.
Experiences of awe, which induce a sense of belonging, are associated with lower levels of stress and a greater sense of well-being.
The 2024 Lancet Commission reported that 45% of dementia cases may be preventable by addressing 14 lifestyle factors.