Ratings You Can Trust

Get science-backed ratings on options to improve your brain health, and explore steps you can take now.

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Evidence rating reflects available research on potential benefit. Null rating indicates lack of available evidence.

Metformin, diabetes drug, and dementia

Metformin

Updated Apr 2, 2018

Evidence

Potential Benefit

Safety

Is Vortioxetine good for your brain?

Vortioxetine

Updated Feb 22, 2018

Evidence

Potential Benefit

Safety

supplements

Nicotinamide Riboside

Updated Feb 13, 2018

Evidence

Potential Benefit

Safety

D-serine activates NMDA receptors, which are involved in synapse formation

D-Serine

Updated Jan 31, 2018

Evidence

Potential Benefit

Safety

centrophenoxine, cholinergic nootropic

Centrophenoxine

Updated Dec 18, 2017

Evidence

Potential Benefit

Safety

Supplements like Citicoline

Citicoline

Updated Nov 30, 2017

Evidence

Potential Benefit

Safety

Glucosamine for joints

Glucosamine

Updated Sep 19, 2017

Evidence

Potential Benefit

Safety

Krill

Krill Oil

Updated Aug 25, 2017

Evidence

Potential Benefit

Safety

Insulin shot

Liraglutide

Updated Jul 27, 2017

Evidence

Potential Benefit

Safety

Supplements - Benfotiamine, relative of thiamine

Benfotiamine

Updated Mar 24, 2017

Evidence

Potential Benefit

Safety

Do N-acetylcysteine supplements help prevent dementia?

N-acetylcysteine

Updated Feb 2, 2017

Evidence

Potential Benefit

Safety

L-theanine supplements

L-theanine

Updated Jan 20, 2017

Evidence

Potential Benefit

Safety

Berberine, an alkaloid, found in the Barberry plant

Berberine

Updated Jan 18, 2017

Evidence

Potential Benefit

Safety

Green Tea Leaves

EGCG

Updated Dec 21, 2016

Evidence

Potential Benefit

Safety

Supplements

Phosphatidylserine

Updated Nov 10, 2016

Evidence

Potential Benefit

Safety

Green Tea

Green Tea

Updated Oct 28, 2016

Evidence

Potential Benefit

Safety

Pig - which cerebrolysin is derived from

Cerebrolysin

Updated Sep 22, 2016

Evidence

Potential Benefit

Safety

Prescription Bottle

Lithium - Pharmaceutical

Updated Sep 21, 2016

Evidence

Potential Benefit

Safety

Firmoss plant

Huperzine A

Updated Aug 30, 2016

Evidence

Potential Benefit

Safety

Nicotine Patch

Nicotine

Updated Aug 24, 2016

Evidence

Potential Benefit

Safety