OUR PORTFOLIO

Our portfolio includes grants and mission-related investments supporting Alzheimer’s drugs in development, biomarkers, prevention programs, and other projects designed to build the capacity of the field. You can explore the programs we have supported using the filter and “Search Database” options in the sidebar.

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816 Projects | 564 Researchers | $395,220,023 Invested

2026

Washington University in St. Louis

Timothy Miller, MD, PhD

Optimizing a Gene-Targeted Therapeutic to Enhance TBK1 Expression in Genetic FTD

  • Funding Amount: $348,007
  • Organization Type:
  • Program: Drug Discovery
  • Target: Other
  • Status: Active

2026

MindImmune Therapeutics, Inc.

Frank Menniti, PhD

MITI-101, a novel antibody therapeutic to treat Alzheimer's disease and related disorders

  • Funding Amount: $5,014,485
  • Organization Type:
  • Program: Clinical
  • Target: Inflammation
  • Status: Active

2025

Superfluid Dx

Bojk Berghuis

Integrating cfRNA and Proteomics with AI for Next-Generation Alzheimer’s Diagnostics

  • Funding Amount: $911,250
  • Organization Type:
  • Program: Diagnostics Accelerator
  • Target: Other
  • Status: Active

2025

Alzheimers Disease Data Initiative (ADDI)

Farhad Imam

The Global Neurodegeneration Proteomics Consortium: V2 expansion for ADNI and other key AD datasets

  • Funding Amount: $1,881,800
  • Organization Type:
  • Program: Diagnostics Accelerator
  • Target: Other
  • Status: Active

2025

Board of Trustees of the Leland Stanford Junior University

Michelle James, PhD

Development of new PET radiotracers for detecting and tracking innate immune activation in the whole body and CNS of Alzheimer's disease

  • Funding Amount: $350,385
  • Organization Type: Academic/Nonprofit
  • Program: Biomarkers
  • Target: Inflammation
  • Status: Active

2025

The University of Edinburgh

Neil McKenzie, PhD, CChem, MSc, BSc(Hons)

“The development and evaluation of a clinical RT-QuIC test for diagnosis of TDP-43 linked Fronto-temporal dementias: A small multicentre trial.”

  • Funding Amount: $144,585
  • Organization Type:
  • Program: Biomarkers
  • Target: Proteostasis/Proteinopathies
  • Status: Active

2025

Emtherapro

Nicholas Seyfried

A novel, accurate plasma proteomic assay for screening and diagnosis of individuals with Alzheimer’s Disease and Alzheimer’s Disease Related Dementia (AD/ADRD)

  • Funding Amount: $499,415
  • Organization Type:
  • Program: Diagnostics Accelerator
  • Status: Active

2025

AviadoBio

Graeme Fielder, MBD, PhD

ASPIRE.FTD: A Phase 1/2 Open-Label, Ascending Dose, Multicenter Study to Evaluate the Safety and Preliminary Efficacy of AVB-101 Administered by Bilateral Intrathalamic Infusion in Subjects With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)

  • Funding Amount: $2,417,356
  • Organization Type:
  • Program: Drug Discovery
  • Status: Active

2025

Icahn School of Medicine at Mount Sinai

Alison Goate, D.Phil.

Development of a Scalable CSF YWHAG:NPTX2 ELISA Assay for Cognitive Prognosis in Early AD

  • Funding Amount: $598,982
  • Organization Type:
  • Program: Biomarkers
  • Target: Synaptic Plasticity/Neuroprotection
  • Status: Active

2025

Vesper Bio ApS

Mads Fuglsang Kjølby

Open-label multiple dosing study in asymptomatic GRN-Frontotemporal dementia patients to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of VES001.

  • Funding Amount: $2,549,203
  • Organization Type:
  • Program: Clinical
  • Target: Synaptic Plasticity/Neuroprotection
  • Status: Active
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