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Krishna Knabe
Director of Communications
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Events
April 12, 2018
Inaugural Memories Matter Benefit Raises $1.2 Million for Alzheimer’s Drug Research
Our inaugural Memories Matter benefit raised $1.2 million for Alzheimer's drug research.
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Initiatives
March 28, 2018
ADDF and Harrington Discovery Institute Invite Applications for 2018 ADDF-Harrington Scholar Award
Harrington Discovery Institute and the Alzheimer’s Drug Discovery Foundation (ADDF) announce a request for proposals for the 2018 ADDF-Harrington Scholar Award.
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Events
March 16, 2018
Kim Campbell Honored at Premiere Women’s Luncheon in Palm Beach, Hosted by Jane Seymour
On Tuesday, March 13, the Alzheimer’s Drug Discovery Foundation (ADDF) honored Kim Campbell for her charitable work at our Premiere Women’s Luncheon at Club Colette in Palm Beach.
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New Grants
March 13, 2018
Funding Supports New Approaches to Treat Multiple Types of Dementia
The ADDF announces two investments in programs targeting mitochondria and the progranulin gene.
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Events
February 20, 2018
ADDF Named an Official Charity Partner of the 2018 New York City Marathon
The Alzheimer’s Drug Discovery Foundation is once again an Official Charity Partner of the 2018 TCS New York City Marathon, which takes place on Sunday, November 4, 2018.
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New Grants
January 8, 2018
$1.8 Million in New Funding Supports Clinical Stage Treatments
The ADDF announces nearly $1.8 million in new funding, which reflects our commitment to advancing drugs in or near human clinical trials.
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New Grants
November 14, 2017
Three New Grants Keep Promising Programs Forging Ahead
The Alzheimer’s Drug Discovery Foundation (ADDF) announces three new investments, all of which are for programs that the ADDF previously funded.
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Research Update
November 1, 2017
New Report Highlights Innovation in Alzheimer’s Clinical Trials
Closing in on a Cure: 2017 Alzheimer’s Clinical Trials Report surveys the 126 drugs in clinical development for Alzheimer’s disease—20% of which received support from the Alzheimer’s Drug Discovery Foundation.
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Events
October 30, 2017
Sharon Sager of UBS Honored for Support of Alzheimer’s Research
Sharon Sager from UBS received The Charles Evans Award at our Eighth Annual Fall Symposium & Luncheon. This year was the largest and most successful in the event’s history, raising over $1.2 million.
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New Grants
October 24, 2017
Innovative Alzheimer’s Combination Therapy Trial Supported by New Joint Funding Initiative
We are jointly funding a new combination therapy clinical trial for Alzheimer’s disease to be conducted by Amylyx Pharmaceuticals.
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Initiatives
October 3, 2017
New Project Co-Funded with Pfizer’s Centers for Therapeutic Innovation
The Alzheimer's Drug Discovery Foundation (ADDF) and Pfizer's Centers for Therapeutic Innovation (CTI) announced joint support for a project that could result in a therapeutic for neurodegenerative diseases.
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Initiatives
September 14, 2017
Dr. Roberta Diaz Brinton Wins Alzheimer’s Drug Discovery Foundation’s Melvin R. Goodes Prize
Dr. Brinton has pioneered a promising neurogenesis therapy for Alzheimer’s disease.
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Research Update
September 13, 2017
18th Annual Conference on Alzheimer’s Drug Discovery Showcases Non-Amyloid Research
Nearly 200 academic and industry researchers came together to share updates on innovative preclinical and clinical-stage Alzheimer’s disease research at the 18th Annual Conference on Alzheimer's Drug Discovery.
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New Grants
September 5, 2017
New Funding Supports Blood Test for Early Alzheimer’s
The ADDF announces two new grants, including support for a blood test designed to detect Alzheimer’s disease in early stages of development and a gene therapy for frontotemporal dementia.
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New Grants
July 11, 2017
Latest Funding Includes Support for Innovative Clinical Trial
The ADDF announces four new grants, including support for an innovative clinical trial, two novel drug programs, and a biomarker for CTE.
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Research Update
June 29, 2017
2016 Annual Report Released
The 2016 Annual Report, titled “From Idea to Impact,” highlights the enormous progress the ADDF has made toward finding effective treatments for Alzheimer’s disease.
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Initiatives
June 7, 2017
ADDF and Science Exchange Launch ADDF ACCESS to Advance Research
New “CRO Finder” Connects Scientists with Specialized Resources
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New Grants
May 15, 2017
$2.6 Million in New Grants Spurs Innovation
We announce 10 new grants totaling over $2.6 million to drive promising new approaches to treating and diagnosing Alzheimer’s and related dementias.
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Events
May 11, 2017
Tad Smith & Sotheby’s Honored at Connoisseur’s Dinner
11th annual gala raises $2.5 million for lifesaving Alzheimer's treatments
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Events
April 27, 2017
Author Sally Quinn Honored at Our Great Ladies Luncheon, Hosted by Judy Woodruff
We raised over $350,000 for life-saving research at our Seventh Annual Great Ladies Luncheon & Fashion Show in Washington, DC, which honored author Sally for her work in the fight against Alzheimer's.
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New Grants
April 24, 2017
ADDF Invests $300,000 to Support Phase 2 Clinical Trial of Epigenetic Therapy
A new investment of $300,000 in Oryzon Genomics continues our support of its groundbreaking epigenetic drug ORY-2001.
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Research Update
April 20, 2017
ADDF-Funded Scientists Discover Two Repurposed Drugs With Promise for Alzheimer’s and FTD
A team of scientists from the Medical Research Council (MRC) in the UK have found two drugs, which block brain cell death and prevent neurodegeneration in preclinical studies. Their findings were published today in Brain.
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New Grants
April 13, 2017
ADDF Funding Advances M3 Biotechnology Toward Clinical Trials
Our new investment in M3 Biotechnology is advancing its drug program toward clinical trials
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New Grants
March 7, 2017
$4 Million in New Grants Support Several First-in-Class Dementia Treatments
We recently awarded eight new grants totaling over $4 million to advance treatments for Alzheimer’s and related dementias. Several of the awards support new approaches to treating these diseases.
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Events
February 3, 2017
ADDF An Official Charity Partner of the 2017 TCS New York City Marathon
We have been chosen as Official Charity Partner of the TCS New York City Marathon for the third year. The race will take place on Sunday, November 5, 2017.
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Initiatives
January 18, 2017
Expanded Partnership Increases Support for Drug Discovery
ADDF and Harrington Institute increase funding and resources for promising Alzheimer’s drug discovery programs.
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Board & Staff
January 10, 2017
Mark Roithmayr Appointed As Our First CEO
Our Board of Governors has appointed Mark Roithmayr as Chief Executive Officer. Mr. Roithmayr is the first person to hold the CEO position at the ADDF.
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New Grants
January 9, 2017
$2.5 Million in New Grants Advance Clinical Trials of Alzheimer’s Treatments
We awarded three new grants in November and December, totaling nearly $2.5 million. The grants represent our commitment to advancing the most promising drugs to clinical trials, the final stages of drug development.
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Events
November 15, 2016
Donald Newhouse Honored for His Efforts to End a Rare Form of Dementia
On November 14, Donald Newhouse received The Charles Evans Award from the ADDF at our Seventh Annual Fall Symposium & Luncheon at The Pierre in New York City. Thanks to the generosity of our donors, the Symposium & Luncheon raised nearly $1 million for drug discovery research.
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New Grants
November 8, 2016
$1.5 Million in New Grant Funding for Promising Treatments
The Alzheimer’s Drug Discovery Foundation awarded three new grants in September and October totaling nearly $1.5 million.
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Initiatives
October 27, 2016
Alzheimer’s Drug Discovery Foundation Launches Expanded Brain Health and Dementia Prevention Website
The streamlined site separates fact from fiction and empowers people to make smarter choices for their brain health.
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New Grants
September 29, 2016
New Clinical Trial Will Test Cancer Drug as Alzheimer’s Treatment
Dr. Howard Fillit, the ADDF's Founding Executive Director and Chief Science Officer, says: "The ADDF is proud to support a clinical trial that holds such promise for Alzheimer's patients. This funding is part of our wider initiative to use the knowledge gained from cancer research to advance effective treatments for Alzheimer's."
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Research Update
September 27, 2016
Experimental Imaging Agent Reveals Concussion-Linked Brain Disease in Living Brain
Protein tracer shows distinctive pattern of brain protein deposition specific to this disease and typically confirmed after death
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New Grants
September 22, 2016
Vivreon Biosciences Awarded Grant to Advance Drug Program Targeting Neuroinflammation
Vivreon Biosciences, LLC has been awarded a preclinical drug discovery grant from the Alzheimer's Drug Discovery Foundation (ADDF) to develop compounds that targets brain inflammation in Alzheimer's disease.
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New Grants
September 21, 2016
$1.7 Million Grant Supports Promising Drug That Targets Cannabinoid Receptor
With a $1.7 million award from the ADDF, a new biotech created by Cleveland Clinic Innovations is developing a novel drug that reduces inflammation in the brain by targeting a cannabinoid receptor.
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Research Update
September 13, 2016
Dr. D. Martin Watterson Wins Second Melvin R. Goodes Prize
Dr. Watterson has identified a number of new classes of Central Nervous System drugs.
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New Grants
September 12, 2016
Three New Grants Support Promising Treatments for Alzheimer’s Disease
The ADDF awarded three new grants in July and August for potential new treatments for Alzheimer's and other dementias.
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Research Update
August 24, 2016
Panel of Experts Calls for Comparative Effectiveness Research
With better evidence, routine medical decisions could help prevent dementia.
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New Grants
July 7, 2016
Five New Grants Fund Promising Treatments & Biomarkers
The ADDF awarded five new grants in May and June 2016, totaling nearly $1.5 million.
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Initiatives
May 13, 2016
Lauder and Newhouse Families Announce New Initiative to Find Treatments for Frontotemporal Dementia
The Lauder Foundation, Leonard A. Lauder, President, and Ronald S. Lauder have committed $5 million, which will be combined with $5 million from the Samuel I. Newhouse Foundation to create The Treat FTD Fund. The fund, a joint program of AFTD and the ADDF, will accelerate clinical trials for FTD over the next decade.
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New Grants
May 10, 2016
Ten New Grants Support Alzheimer’s Drug Discovery and Biomarker Development
The ADDF has awarded 10 new grants to researchers developing drugs for neurodegenerative diseases and biomarkers to detect their onset and progression.
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Events
April 29, 2016
Ronald S. Lauder Honored at Connoisseur’s Dinner
Annual Gala Raised over $3.25 million for Alzheimer’s Treatments
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Events
April 14, 2016
Trish and George Vradenburg Honored at Great Ladies Luncheon, Hosted by Chris Wallace
Sixth Annual Great Ladies Luncheon & Fashion Show most successful in event's history
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Events
March 9, 2016
ADDF Again Named an Official Charity Partner of the 2016 TCS New York City Marathon
For the second year in a row, the ADDF has been chosen as an Official Charity Partner of the 2016 TCS New York City Marathon. The race will take place on Sunday, November 6, 2016.
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New Grants
February 25, 2016
Five New Grants Support Drug Discovery and Prevention
Grants awarded in the first two months of 2016 support researchers in the U.S. and Middle East pursuing drug programs, prevention studies, and research to accelerate clinical trials.
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Initiatives
February 2, 2016
ADDF Joins BIRAX Regenerative Medicine Initiative
The Alzheimer's Drug Discovery Foundation (ADDF) has joined the BIRAX Initiative, which recently issues its third call for proposals. BIRAX brings together British and Israeli scientists to tackle some of the world’s most challenging diseases including cardiovascular and liver disease, diabetes and Parkinson’s.
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Initiatives
January 12, 2016
PsychoGenics and the ADDF Announce a Risk-Sharing Partnership for Preclinical Studies
We are partnering with PsychoGenics Inc. to bring its services to our grantees working on preclinical Alzheimer’s drug discovery programs.
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New Grants
January 5, 2016
Five New Research Grants Support Clinical and Early-Stage Programs
Funded Researchers are pursuing diverse targets to treat Alzheimer's disease.
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Board & Staff
December 29, 2015
New Members Deepen Research & Investment Expertise of ADDF Boards
At the December joint meeting, the ADDF Boards of Governors and Overseers welcomed seven new members.
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Events
November 10, 2015
Margaret and Daniel Loeb Honored at Our Sixth Annual Fall Symposium & Luncheon
On November 9, Margaret and Daniel Loeb received The Charles Evans Award at our Annual Fall Symposium & Luncheon, which raised more than $1 million.
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New Grants
November 4, 2015
New Grant Supports AlzeCure’s Work on Neurorestorative Drug
AlzeCure Foundation announced today that it has been awarded a grant from the ADDF to support the further development of its small molecule neurorestorative project.
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Research Update
September 16, 2015
Dr. Frank Longo Wins Inaugural Melvin R. Goodes Prize
Dr. Longo's pioneering approach may soon lead to new disease modifying drugs.
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New Grants
August 26, 2015
ADDF and Harrington Discovery Institute Announce 2015 Award Recipients
Collaboration advances development of therapeutics for the treatment of Alzheimer’s Disease.
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Initiatives
August 24, 2015
ADDF to be Featured in Upcoming Episode of Innovations with Ed Begley Jr.
The ADDF is featured in an episode of Innovations with Ed Begley Jr. on the Discovery Channel.
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Initiatives
August 12, 2015
Goodes Family & The ADDF Create New Prize for Alzheimer’s Drug Development Researchers
Melvin R. Goodes Prize supports innovative projects by top researchers while honoring the legacy of the former Warner-Lambert CEO.
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Initiatives
August 6, 2015
Carmel Valley, California Winery Launches Two New Wines to Benefit the ADDF
Jarman Wines, a winery in Carmel Valley, will introduce two premium varietals to benefit the ADDF and to honor the matriarch of the family whose name graces the wines created for her.
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Research Update
July 30, 2015
Grantees at Lou Rovo Center for Brain Health Recruiting for New Alzheimer’s Disease Trial
Cleveland Clinic Lou Ruvo Center for Brain Health is recruiting participants for a trial to determine if treatment with rasagiline improves brain glucose metabolism and memory.
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Events
May 4, 2015
Alzheimer’s Drug Discovery Foundation Connoisseur’s Dinner Raises $2.8 Million
On April 27, 2015, Susan Stroman hosted the ADDF's Ninth Annual Connoisseur’s Dinner, which raised more than $2.8 million for Alzheimer's drug discovery and development.
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Events
April 17, 2015
Diane Rehm Hosts 2015 Great Ladies Luncheon & Fashion Show
Renowned journalist and NPR host Diane Rehm spoke about the need to increase support for drug discovery for Alzheimer's at the ADDF's Annual Great Ladies Luncheon & Fashion Show.
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New Grants
April 9, 2015
Asceneuron Awarded Alzheimer’s Drug Discovery Foundation Grant
Asceneuron SA, an emerging leader in small molecule therapeutics targeting tauopathies for Alzheimer's and related neurodegenerative diseases, was awarded a $325,000 grant from the ADDF to support the development of its tau modulators.
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New Grants
March 17, 2015
GliaCure Receives $1 Million Grant for Alzheimer’s Clinical Trial
The ADDF awarded $1 million to GliaCure to co-fund a Phase 1b clinical trial in patients with mild to moderate Alzheimer's disease.
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Events
March 3, 2015
Alzheimer’s Drug Discovery Foundation an Official Charity Partner of 2015 TCS New York City Marathon
The ADDF is pleased to announce that it is an Official Charity Partner of the 2015 TCS New York City Marathon.
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Initiatives
February 11, 2015
ADDF Teams Up with Pfizer CTI to Support Discovery of Drugs for Alzheimer’s Disease
The ADDF and Pfizer’s Centers for Therapeutic Innovation are collaborating to advance the development of new small-molecule drugs for Alzheimer’s disease and related dementias.
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New Grants
January 28, 2015
New Approach to Delay Alzheimer’s Dementia Onset to Be Tested in Phase-3 Clinical Trial
The ADDF announced today a grant to AgeneBio in support of an FDA-registered Phase 3 clinical trial of AGB101, a new therapeutic treatment for amnestic mild cognitive impairment.
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New Grants
December 18, 2014
New Funding for Italian Biotechnology Company Exploring Novel Drugs for Alzheimer’s Disease
The ADDF has awarded a follow-on grant to Axxam to further develop small molecule drugs to treat Alzheimer's disease by targeting inflammation.
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New Grants
December 11, 2014
Erectile Dysfunction Drug to Be Tested as Dementia Treatment
The ADDF and the Alzheimer's Society UK announced new funding to explore the possibility of using tadalafil, a commonly prescribed drug which treats erectile dysfunction, as the next treatment for dementia.
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Events
November 4, 2014
Alzheimer’s Drug Discovery Foundation Honors B. Smith at Fifth Annual Fall Symposium & Luncheon
Former model and restaurateur B. Smith was honored by the ADDF at its Fifth Annual Fall Symposium & Luncheon for raising public awareness and critical funds to combat Alzheimer's disease.
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Initiatives
September 10, 2014
New Platform Powered by OnDeckBiotech Connects Researchers with Drug Discovery Expertise
The ADDF and OnDeckBiotech announced the relaunch of ADDF ACCESS as a new and improved platform to connect scientists with a virtual network of contract research organizations.
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Initiatives
June 26, 2014
Leading Foundations Publish Recommendations to Accelerate Drug Repurposing
A peer-reviewed publication from the ADDF and The Michael J. Fox Foundation for Parkinson’s Research offers strategic insight on how organizations can advance the repurposing of FDA-approved drugs for treating neurodegenerative diseases.
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Initiatives
June 26, 2014
Alzheimer’s Drug Discovery Foundation and OnDeckBiotech Partner to Expand ADDF ACCESS Network
The ADDF and OnDeckBiotech announced a strategic partnership to provide a new platform technology for ADDF ACCESS. Utilizing OnDeckBiotech's technology, ADDF ACCESS will increase the efficiency of contracting drug development services.
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New Grants
June 9, 2014
ADDF and Harrington Discovery Institute Announce 2014 Award Recipients
Researchers from The Ohio State and Emory Universities will be the first recipients of drug discovery funding and innovation support from a new partnership between the ADDF and Harrington Discovery Institute.
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Research Update
May 2, 2014
Alzheimer’s Drug Discovery Foundation Raises $1.1M for New Clinical Trial in Alzheimer’s
The ADDF raised more than $1.1 million at its Eighth Annual Connoisseur's Dinner to go to Jeffrey Cummings, MD in support of a clinical trial for a repurposed drug for treating Alzheimer's disease.
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Initiatives
April 23, 2014
ADDF Launches New Cognitive Vitality Site to Meet Critical Need in Alzheimer’s Prevention
The ADDF launched Cognitive Vitality, an online resource that provides overviews and analyses of dementia prevention strategies.
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Initiatives
March 24, 2014
Leading Foundations Partner to Accelerate Critical Biomarker Research in AD and Related Dementias
In partnership with the ADDF, the Alzheimer's Disease and Dementia Initiative at the New York Academy of Sciences has awarded a grant to Blaine Roberts, PhD, at The Florey Institute of Neuroscience and Mental Health.
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Initiatives
March 14, 2014
New Partnership to Provide Drug Discovery Resources for Neurofibromatosis Research Community
The ADDF and the Children's Tumor Foundation announced a partnership to provide CTF's community of neurofibromatosis researchers access to the ADDF ACCESS program.
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New Grants
March 11, 2014
ADDF and AFTD Award Grants Funding Research on Investigational Therapies to Treat Dementia
The ADDF and The Association for Frontotemporal Degeneration announced the recipients of their seventh annual partnership awards program to accelerate drug discovery for frontotemporal degeneration.
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New Grants
February 27, 2014
ADDF and FMM Partner to Support Novel Research for Mitochondrial-Directed Therapies
The ADDF and the Foundation for Mitochondrial Medicine awarded $200,000 to James Bennett, M.D., Ph.D. to further research gene therapy of mitochondrial protein in mice with experimental Alzheimer's disease.
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Initiatives
January 28, 2014
ADDF and W. Garfield Weston Foundation Collaborate to Fund Clinical Trial in Alzheimer’s
The ADDF and The W. Garfield Weston Foundation announced a funding collaboration to support a clinical trial investigating the potential for hypertension drugs to slow Alzheimer's disease progression.
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Initiatives
January 24, 2014
Foundations Partner on $3M Initiative to Accelerate Research + Discover Treatments for Alzheimer’s
The ADDF and the Alzheimer’s Society (UK) announced a new partnership that intends to fund projects up to $1.5 million each focused on drug repurposing.
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Initiatives
November 6, 2013
ADDF Expands its ADDF ACCESS Program to Improve Quality and Efficiency of Drug Research
The ADDF expanded its ACCESS program to provide a virtual network of drug discovery experts and contract research organizations that can expedite the development of therapies for neurodegenerative diseases.
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Events
October 24, 2013
The ING New York City Marathon: Who Runs? Chris Johnson.
Chris Johnson, son of legendary New York Giants Running Back Ron Johnson, has taken up the cause to find a cure for Alzheimer's disease.
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Initiatives
October 24, 2013
ADDF Partners with Harrington Discovery Institute at University Hospitals Case Medical Center
The ADDF and the Harrington Discovery Institute's partnership leverages their combined expertise and resources to advance promising Alzheimer's drug discovery projects.
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Initiatives
August 26, 2013
The Horizon Tank: A Gomez-Gracia Limited Edition, Designed for the ADDF
London-based luxury designer Patricia Gomez-Garcia created this limited edition item in support of the ADDF.
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Events
August 20, 2013
ADDF Presents its September 2013 14th International Conference on Alzheimer’s Drug Discovery
The ADDF presents its annual fall conference on Alzheimer's drug discovery on September 9-10, 2013 in Jersey City, New Jersey.
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Initiatives
July 1, 2013
The Alzheimer’s Drug Discovery Foundation Launches ADDF Access
The ADDF launched the ADDF ACCESS program to give academic and small biotechnology communities online access to industry standard preclinical drug discovery and development services.
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New Grants
June 12, 2013
ADDF Supports Madera Biosciences to Advance Small Molecule Drugs that Upregulate APOE
The ADDF announced that it has awarded follow-on funding to Madera Biosciences, Inc. to further develop its small molecule drugs designed to clear accumulated beta-amyloid from the brain.
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New Grants
April 24, 2013
Research Foundations Collaborate to Fund Ph 1 Study of Cancer Drug In Alzheimer’s Disease Patients
The ADDF and BrightFocus Foundation announced a funding collaboration to support a Phase I clinical trial to evaluate the cancer drug bexarotene as a treatment for Alzheimer's.
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New Grants
March 25, 2013
Alzheimer’s Drug Discovery Foundation and Lewy Body Dementia Association Award Two Grants to Support
The ADDF and the Lewy Body Dementia Association awarded two grants of $100,000 each to support research on developing biomarkers for dementia with Lewy bodies.
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New Grants
March 6, 2013
Alzheimer’s Drug Discovery Foundation Awards Grant To Cohbar To Develop A Novel Peptide Therapeutic
The ADDF has awarded $205,260 in funding to CohBar Inc. to develop a mitochondrial peptide, which has been shown to have neuroprotective effects.
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Research Update
February 28, 2013
Research Foundations Collaborate to Fund Repository of Promising CNS-Active Compounds
The Alzheimer's Drug Discovery Foundation, Beyond Batten Disease Foundation, and the National Multiple Sclerosis Society announced a funding collaboration to support the creation of the Collaborative CNS Screening Initiative.
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Research Update
February 5, 2013
Medicare Panel’s Failure to Recommend Payment for New Alzheimer’s Diagnostic Brain Imaging…
Howard Fillit, MD and George Vradenburg of USAgainstAlzheimer's issued a joint statement, responding to MEDCAC's opinion to not support Medicare reimbursement for PET amyloid imaging scans.
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Research Update
April 6, 2012
ADDF’s Seed Funding Leads to FDA Approval of Amyvid™, First Diagnostic Test for Alzheimer’s Disease
The FDA has approved Amyvid™, the first diagnostic test for Alzheimer's disease, for which the ADDF provided critical seed funding.
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Krishna Knabe
Director of Communications
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