The ADDF offers funding to researchers in both nonprofit and for-profit organizations for drug discovery, clinical trials, and biomarker development. Visit our Research Priorities for specific information about our interests.
ADDF FUNDING PORTAL
The majority of funding is provided through four Core Requests for Proposals (RFPs). Letters of intent are accepted and reviewed on a rolling basis during four cycles each year, with corresponding deadlines for invited full proposals. Check back throughout the year for additional funding opportunities through our collaborations with non-profit, government, and industry partners.
CORE REQUESTS FOR PROPOSALS
Program to Accelerate Clinical Trials (PACT) RFP
This RFP funds early-stage clinical trials through phase 2 for novel drug candidates, proof-of-concept trials in patients for repurposed/repositioned drugs, and regulatory studies for IND/CTA preclinical packages and drug manufacturing for later stage trials.
Neuroimaging and CSF Biomarker Development RFP
This RFP supports the development and validation of neuroimaging and CSF biomarkers to enhance clinical trials for Alzheimer's disease, related dementias, and cognitive aging.
Prevention Beyond the Pipeline RFP
This RFP supports comparative effectiveness research, prevention clinical trials, and epidemiological studies that probe whether the use or choice of drugs alters the risk for dementia or cognitive decline.
Drug Discovery RFP
This RFP supports programs advancing lead molecules to clinical candidate selection or building preclinical evidence in relevant animal models for repurposed/repositioned drugs.
OTHER REQUESTS FOR PROPOSALS
The Treat FTD Fund RFP
Supports clinical development of novel and repurposed drugs for FTD disorders through proof-of-concept and pilot proof-of-mechanism trials or phase 0/1 studies in healthy volunteers assessing pharmacodynamic outcomes. This program is in partnership with The Association for Frontotemporal Degeneration.
Letter of Intent: November 9, 2018
Diagnostics Accelerator: Peripheral Biomarkers RFP
Seeks to support proof-of-principle and validation studies for peripheral biomarkers and novel diagnostic technologies for Alzheimer's disease and related dementias. Funding and committed project support by from industry experts is provided through a collaboration between the ADDF, Bill Gates, and other partners.
OTHER ADDF FUNDING OPPORTUNITIES
Supports NIA and NINDS grant proposals in NIH format that were scored but not funded, which fall within our mission and research priorities.
Supports scientific conferences that are relevant to our mission with grants up to $10,000. For more information, email firstname.lastname@example.org with a brief summary of your conference
Stay Updated on Upcoming Deadlines and RFP Announcements