Before Getting Started


Step 1

Submit a Letter of Intent (LOI) through the ADDF Funding Portal.

  1. Fill in contact and project information (e.g. title, duration, amount requested).
  2. Include project details as follows:
    • Scientific Rationale and Background (300 words maximum)
    • Specific Aims (300 words maximum)
    • Summary of Key Supporting Data (300 words maximum)
  3. Required for Resubmissions: you will be asked to attach a written point-by-point response to each of the reviewers' comments and upload as "Applicant Response to Reviewers."

After your LOI is submitted, it will be reviewed to evaluate whether the proposed project is consistent with the ADDF's mission and funding priorities. LOI decisions will be sent within three weeks of submission. Only invited full proposals will be accepted.


Step 2

If invited, submit a full proposal through the ADDF Funding Portal.

Information you submitted with your LOI will carry over to the full proposal. This information can be edited or expanded upon at this stage.

In addition to these auto-filled sections, you will be asked to write an Executive Lay Summary (300 words maximum) and a Biographical Summary for the Principal Investigator (300 words maximum). The remainder of the application is as follows below.

  1. Body of the Application: Review the instructions for the required sections and forms for the Body of the Application. Compile the four sections below into a single PDF and upload as "Body of the Application."
  2. Business Packet (required for all biotech companies): In the event that these materials are not available, please provide justification. Please compile into a single PDF and upload as "Business Packet."
    • Statement of Need
    • Business Plan or Corporate Strategy – include company description and history, mission statement, market analysis, risk analysis, milestones, scientific and financial goals, and future plans
    • Description of Management Structure – include a list of board members
    • Capitalization Table
    • Financial Statements – balance sheet, income statement, cash flow statement
    • Company's Current Annual Budget
    • Description of Investors to Date
    • Intellectual Property Summary – note all IP linked to the project, including pending or granted IP, and if you expect to generate new IP; if the patent(s) are openly available online, please include the link(s) in lieu of attaching full files.
  3. Supplemental Materials: All of the following are optional. If not submitting Supplemental Materials, upload a PDF stating "N/A." Otherwise, compile all the materials into a single PDF and upload as "Supplemental Materials." These materials can include:
    • IRB-ready clinical protocols
    • Quotes from vendors or contract research organizations (CROs). Please include competitive quotes from more than one vendor where possible. Visit ADDF ACCESS to work directly with a concierge who can help you obtain competitive quotes from quality vendors.
    • Letters of support/collaboration
    • Figures that cannot be embedded into the body of the application but are directly relevant to the application and may be helpful to the review committee.

Limit the number of additional attachments included in the Supplemental Packet. You may also include unpublished manuscripts. Publications and patents that are openly available online should be linked in lieu of attaching the full files. Do not include presentation decks or full patents.


ADDF FUNDING PORTAL

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If you have any questions about the online application system or process, please contact the Grants and Mission-Related Investments Team at grants@alzdiscovery.org.