Alzheimer's Matters, the official blog of the ADDF, features insights, perspectives and commentary on current topics of interest in Alzheimer's disease and related drug discovery.

Striding Toward $100 Million on Giving Tuesday


Since 1998, the ADDF has invested $97 million in critical research and—with your #GivingTuesday donation—we will reach $100 million this year.

What Does the Failure of Solanezumab Mean?


Eli Lilly announced that its Alzheimer's drug solanezumab failed in its last phase 3 clinical trial. Howard Fillit, MD, discusses what this means for the field and for patients, and where we go from here.

Looking Ahead on World Alzheimer’s Day


On World Alzheimer’s Day, we celebrate the progress made and look toward the future. 

Advancing Epigenetics: A New Approach to Treating Alzheimer’s Disease


Executive Director Howard Fillit, MD, discusses epigenetic treatments, one of the newest and most promising areas of our portfolio. 

My Marathon Journey with the ADDF


Ernest Scheyder, a returning member of the ADDF’s TCS NYC Marathon team, shares why he is running for Alzheimer’s research and how you can help him and the rest of our dedicated runners.

ADDF-Funded PET Imaging Makes Clinical Trial Success Possible


For the first time, a treatment has reduced amyloid beta plaques in the brains of patients with Alzheimer’s disease. 

The Enduring Legacy of NFL Star Tommy Mason


Karen Mason reflects on her late husband, Tommy Mason, whom she describes as "larger than life," a trait that remained even as he endured the effects of Alzheimer’s.

Research Update: Dr. Carmela Abraham Founds New Biotech


With support from the ADDF, Carmela Abraham, PhD, recently founded a biotech company to accelerate the development of a new class of drugs to combat Alzheimer’s disease

Alzheimer’s Drug Featured in Time Was Made Possible by the ADDF


Grantee Dr. Frank Longo's promising new drug to treat Alzheimer's is on the cover of Time magazine

2015: Our Most Successful Year


Executive Director Howard Fillit, MD, looks back at 2015—our most successful year ever—and thanks the supporters and scientists who made it possible